The concentration of 6-keto-prostaglandin F1α is markedly elevated at the site of blastocyst implantation in the rat

TG Kennedy, J Zamecnik - Prostaglandins, 1978 - Elsevier
The initiation of blastocyst implantation in the rat is indicated by localized increases in
endometrial vascular permeability at the sites where blastocysts are present. The
concentrations of 6-keto-prostaglandin F 1α (6-keto-PGF 1α), a stable metabolite of
prostaglandin I 2 (PGI 2), were measured by gas chromatography-mass spectrometry in the
areas of increased endometrial vascular permeability (uterine dye sites), and compared with
those in the remainder of the uterus (uterine non-dye sites). For rats killed either on the …