Silencing of circ_0009910 inhibits acute myeloid leukemia cell growth through increasing miR-20a-5p

L Ping, C Jian-Jun, L Chu-Shu, L Guang-Hua… - Blood Cells, Molecules …, 2019 - Elsevier
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, which is
aggressive cancer. CircRNAs are abundantly expressed in the hematologic malignancy
cells. In this study, we aimed to investigate the expression profiling of circRNAs in AML. We
performed circRNA-sequencing to identify differentially expressed circRNAs in bone marrow
samples from AML patients and iron-deficiency anemia (control). Furthermore, we found that
circ_0009910 was significantly upregulated in AML patients compared with iron-deficiency …